# Relapses Keywords: multiple sclerosis, relapses, neurological symptoms, inflammation, disease activity, Uhthoff phenomenon, MS therapy > This page provides an overview of relapses in multiple sclerosis, their symptoms, causes, and significance as indicators of disease activity. It highlights the importance of early treatment and monitoring to manage MS effectively and maintain quality of life. ## Details - [Relapses as Indicators of Disease Activity](#): Relapses signal active inflammation in multiple sclerosis, causing disruptions in nerve signal transmission and neurological symptoms. - [Symptoms of a Relapse](#): Symptoms vary in intensity and may include sensory disturbances, vision problems, coordination issues, and speech difficulties. - [Uhthoff Phenomenon](#): Temporary worsening of symptoms due to increased body temperature, often mistaken for a relapse. - [Criteria for a True Relapse](#): Defines the clinical conditions for diagnosing a relapse, including duration, recurrence, and exclusion of other causes. - [Importance of Early Intervention](#): Early treatment of inflammation and relapses is crucial to preserve brain health and prevent disease progression. - [Relapses Visualized as Iceberg Peaks](#): Relapses represent visible disease activity, while underlying inflammation remains hidden and detectable only via MRI. - [Starting Therapy After First Relapse](#): Early therapy initiation is recommended to stabilize the disease and improve long-term outcomes.